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Drug discovery’s weakest link? Why synthesis is the critical bottleneck in the age of AI

In depth editorial article published by Innovations in Pharmaceutical Technology, introducing cluster synthesis as a major breakthrough enabling acceleration of small molecule discovery.

While artificial intelligence (AI) now accelerates molecular design at unprecedented speed, laboratory synthesis continues to lag behind, limiting the impact of digital innovation. Emerging frameworks such as AI-driven orchestration and cluster synthesis offer a path to reshape how laboratories align design with execution.